Cardrine - GW501516 (HADES)

Suggested Serving: 1-2 CAPSULES
Dietary Supplement: 60 CAPSULES
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Category: Sarms


Cardarine GW5051516 SARMs Profile                                               

Drug class: SARMs (Selective Androgen Receptor Modulators)

Half-life: Approximately 24 hours

Chemical formula: C21H18F3NO3S2

Cardarine (also known as GW-501516, GSK-516, and in the market as Endurobol) is a receptor agonist which Ligand Pharmaceuticals and GlaxoSmithKline (GSK) developed. It is used to enhance physical performance and different activities of the body.

Cardarine is a type of metallic modulator chemical that boosts metabolism and the burning of fats. It is used to prevent obesity and diabetes and increase the body’s physical performance. There is no scientific evidence of its safety. So, it is banned by the World Anti-Doping Agency (WADA) as it might be dangerous.

What are SARMs or Selective Androgen Receptor Modulators?

Selective Androgen Receptor Modulators (SARMs) are therapeutic chemicals that have a similar mechanism to other anabolic steroids, but some unique properties of SARMs make them better than steroids. They bind to androgen receptors and stimulate their activity. SARMs have proved quite effective against many diseases and for the growth of specific tissues without affecting others. To date, almost all SARMs are under investigation.

History and development of Cardarine GW501516:

GW5051516 was developed initially during a search collaboration between GSK (GlaxoSmithKline) and Ligand Pharmaceuticals in 1992, and it was published in 2001. GSK and Ligand Pharmaceuticals used combinatorial chemistry and structure-based drug design for its development.

In 2000, it was reported that GSK had begun the trial for phase 1 hyperlipidemia, followed by a phase 2 trial in 2002. Ligand Pharmaceuticals earned $1 million in 2003 due to phase 1 development.

By 2007, the clinical and other studies of GW5051516 for diabetes, obesity, dyslipidemia, and cardiovascular diseases were completed. The development of GW5051516 was stopped after some time because later, it was found that this drug caused rapid cancer development in animals.

How does Cardarine GW501516 work?

Cardarine is made of monocarboxylic acid. It is a member of 1,3-thiazoles of an organofluorine compound. GW5051516 binds with the group of proteins (PPARδ receptors) present in muscles and fatty acids in the body. It may activate these receptors and boost your muscle strength. Cardarine has a half-life of about 24 hours, which means it will stay for a long time in your body. Generally, SARMs take a long time to flush out of your body; this is why you should stay pretty regular with your exercising routine if you’re consuming any SARMs. Regular consumers of Cardarnie claim that it might positively affect the body’s vascular system.

Benefits of Cardarine:

Fat loss:

Cardarine affects glucose metabolism by switching it with fatty acids and thus boosts lipid metabolism and enhances the fat-burning process. In this way, the body utilises fats as a primary energy source, increasing lipid metabolism or fat-burning.

Cholesterol improvement:

Cardarine has proved to have cardioprotective properties. Studies have proven that HDL levels increase by 17% and LDL cholesterol levels lower by 7% in the body after using GW5051516, which might decrease the risk of a heart attack.

Muscle endurance:

GW5051516 converts fast-twitch fibres into slow-twitch fibres, which are more efficient in oxygen utilisation. Muscle endurance is enhanced due to increased vascularity, which helps you during your workouts. It has been proven helpful for athletes. A study on mice showed a 68% increase in muscle endurance in 3 weeks.

Muscle hypertrophy:

Cardarine GW5051516 can enhance slight lean muscle mass. There is evidence of increasing lean mass markedly by using 10mg of Cardarine per day for two weeks.

Does not affect testosterone level:

GW5051516 may not affect your testosterone level, so it doesn’t cause lethargy and hair loss in the users. Women can also use Cardarine to lose fat. Although it does not cause a masculinisation effect, it is still not very safe.

Also, Cardarine activates the PPARδ receptors, which reduces oxidative damage to blood vessels.

How to take Cardarine GW5051516?

Cardarine GW5051516 has not been approved as a medication by FAD, so there are no proper guidelines. However, studies have shown that it can be consumed about 10 mg to 20mg per day for 6-8 weeks. You can use both capsulated or powdered forms of the drug.

What are the Side effects of Cardarine GW5051516:

Although it has been proven effective against fat loss and muscle enhancement, it still has some dangerous side effects on your body. Some of the side effects are:


The development of Cardarine after 2007 was stopped because some tests and trials proved its role in causing cancer. Tumours were found in the skin, eyes, tongue, liver, stomach, bladder, uterus, and testes.

Toxicity in the liver:

In recent studies in humans, GW5051516 showed fluctuations in ALT and AST enzyme levels in the liver and can cause liver toxicity. Cardarine has also been associated with increased risks of heart attacks.


Cardarine may have a stimulating effect on the central nervous system (CNS) and increase adrenaline productivity. It can be avoided by taking the dosage in the morning so that CNS regulates during the day.

Where can you buy it:

You should first know all the essential information about Cardarine (GW5051516 or Endurobol) if you are willing to use it for losing fat and enhancing muscle strength. Get in touch with the team member of your desired UK SARMs store beforehand if need it. Always consult your doctor before taking any supplements.

To conclude, if you and you are planning to buy SARMs UK especially Cardarine GW501516 then you are in the right spot by visiting our SARMs store. Please do consider everything above before the purchase and if you need any further assistance don’t hesitate and drop us a line and we will be happy to assist to best possible way.


  1. Yazdi, P. (2021, November 3). What is Cardarine (GW501516)? + side effects, dangers. SelfDecode Drugs. Retrieved February 2, 2022, from https://drugs.selfdecode.com/blog/gw501516-cardarine/
  2. Coleman, S. (2022, February 1). Cardarine (GW501516) review 2022: Results, Alternatives & Risks. American Professional Supplements Advice. Retrieved February 2, 2022, from https://www.eapsa.org/supplements/cardarine-review/
  3. MD, W. (2022). Cardarine: Overview, uses, side effects, precautions, interactions, dosing and reviews. WebMD. Retrieved February 2, 2022, from https://www.webmd.com/vitamins/ai/ingredientmono-1648/cardarine-%5Bfast-facts%5D
  4. Bodybuilding, I. (2022, January 25). Cardarine (GW-501516): Dosage, Side Effects & before and after pictures. Inside Bodybuilding. Retrieved February 2, 2022, from https://insidebodybuilding.com/cardarine/
  5. Foundation, W. (2021, August 30). GW501516. Wikipedia. Retrieved February 2, 2022, from https://en.wikipedia.org/wiki/GW501516
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    Posted on 24.01.2023
    Steven Race