YK-11 SARMs Profile
Drug Class: Selective Androgen Receptor Modulators (SARMs)
Half-Life: Approx. 24 Hours
Chemical Formula: C25H34O6
YK-11 (Myostatin Inhibitor) is a synthetic steroid related to 5-α-dihydrotestosterone, which is an androgenic hormone and partial agonist at the Androgen receptor (AR). YK-11 is a member of the selective androgen receptor modulators (SARMs) family and is also known as the myostatin inhibitor because of its activity against myostatin (a protein that constrains muscle growth). Currently, YK-11 is the only SARM having the maximum potential of increasing Follistatin (FST) expression. It wouldn’t be wrong to say that YK-11 can be a game-changer in your bodybuilding journey!
What Are SARMs?
Androgenic drugs have long been in use mainly for muscle building, but now there is an alternative class of drugs known as selective androgen receptor modulators (SARMs), which is better tolerated. Selective androgen receptor modulators (SARMs) are the most recent class of drugs having androgenic activity. SARMs are agonists at androgen receptors and activate them to boost muscle growth and anabolic activity. Therefore, SARMs can increase muscle mass and decrease body fat. Selective androgen receptor modulators and steroids have the same clinical activity, but a narrow spectrum of adverse effects makes SARMs a better alternative.
History and Development of YK-11:
In 2011, YK-11 was developed for the first time in Japan. It is a derivative of 5-α-dihydrotestosterone, the natural androgenic hormone. Chemically it is related to steroids having a molecular mass of 430.541 gmol-1.
How Does YK-11 Work?
Being the derivative of 5-α-dihydrotestosterone (DHT), YK-11 interacts with the androgen receptor. Androgen receptors are cell-surface proteins that induce gene expression to develop secondary male sex characters. However, it does not induce N/C interaction, which is essential for the complete activation of androgen receptors. So, yk11 is a partial agonist at the androgen receptor and enhances the catabolic activity in the body. Also, yk11 is a potent activator of the FST gene that encodes Follistatin, an autocrine glycoprotein that binds activin and inhibits myostatin. Myostatin is a muscle growth inhibitor. In short, the myostatin inhibitory effect of YK-11 accounts for its anabolic activity leading to enhanced muscle growth. Research revealed that the differentiating myogenic activity of YK-11 is far greater than dihydrotestosterone (DHT).
What are the Benefits of YK-11?
YK-11 is associated with many health benefits, which are as follows:
Improve Bone Density:
Research has revealed that YK-11 played a significant role in enhancing bone density and osteoblast differentiation. This is because of its capacity to unite with androgen receptors. In 2018, a study on MC3T3-E1 mouse osteoblast cells revealed an increased level of osteoprotegerin and osteocalcin in YK-11 treated cells. Further, it was observed that androgen-mediated osteoblast differentiation is due to activating the Akt/PKB signaling pathway.
Increase muscle mass:
This benefit owes to the ability of yk11 to induce the expression of Follistatin, an inhibitor of myostatin, which builds muscle mass. Its partial agonist activity at the androgen receptor is the key regulator of muscle mass. Whether its use is safe for muscle building is still a mystery.
Another significant benefit of using YK-11 is that it enhances body strength and durability, allowing users to elevate heavyweights and rapidly reach their fitness goals.
Reduction In Fat Mass:
Using YK-11 also allows a user to reduce their body fat. YK-11 stimulates lipolysis (the process of breakdown of fat), making it a good choice for those looking to reduce body fat.
How to take YK-11 SARM:
Commonly, the recommended dosage of YK-11 is 5 mg per day orally. This can be taken either with or without a meal. YK-11 is a highly influential compound and should only be taken by those who have experience with supplements. Many athletes and bodybuilders have pleaded that they get outstanding results when taking a 10 to 15 mg per day dose of YK-11. They report minor side effects of using this dose for approximately 8 weeks.
But it is best for beginners to start with a lower dosage and gradually increase if needed.
What Are the Side Effects of Using YK-11?
Before using yk11, knowing its significant side effects is vital as it has powerful myostatin inhibiting effects. Some of the most common adverse effects are explained below:
Hair Loss: Using YK-11 can cause hair loss. The reason behind this is an increased DHT level.
Increased Cholesterol Level: Before starting YK-11, consult your doctor if you have already experienced increased cholesterol. Because it may lead to atherosclerosis and heart complications, that’s why it is crucial to keep your LDL cholesterol level below 130 mg/dL and your HDL cholesterol level above 35 mg/dL.
Acne: Increased androgen levels by excess use of YK-11 can cause acne.
Stiffness And Joint Pain: A user may report pain and stiffness in joints if he has increased progesterone levels in the body using YK-11.
Lethargy: After using YK-11, some people also report lethargy due to low testosterone levels in the body. It is also due to your body’s testosterone production being suppressed with SARMs.
Where Can You Buy YK-11 Online?
It can be a challenging task to get genuine SARMs products. You should always verify that the product you’re purchasing from online SARMs store is authentic and 100% certified. Many commercial SARMs products contain insufficient or incorrect product formulations. There is always a risk of prohormones or steroids in such low-quality products.
To receive a top-quality product, you can purchase it online from reliable and trusted sources like our UK SARMs store with a certificate of analysis for each product. Always consult your physician before you buy SARMs online and taking any dietary supplementations.
To conclude, if you and you are planning to buy SARMs UK especially YK11 then you are in the right spot by visiting our UK SARMs store. Please do consider everything above before the purchase and if you need any further assistance don’t hesitate and drop us a line and we will be happy to assist to best possible way.
1. Kanno, Y. (2013). Selective androgen receptor modulator, YK11, regulates myogenic differentiation of c2c12 myoblasts by follistatin expression. Biological & pharmaceutical bulletin. Retrieved January 26, 2022, from https://pubmed.ncbi.nlm.nih.gov/23995658/
2. Foundation, W. (2021, March 29). YK-11. Wikipedia. Retrieved January 26, 2022, from https://en.m.wikipedia.org/wiki/YK-11
3. Lakes, F. (2021, October 7). YK11 Sarms Review: YK11 benefits, cycle, side effects, before and after results. Fingerlakes1.com. Retrieved January 26, 2022, from https://www.fingerlakes1.com/2021/10/06/yk11-sarms-review-yk11-benefits-cycle-side-effects-before-and-after-results/
4. Digital, S. (2021, November 10). YK11 results dosage, side effects, before and after Best Sarms for sale 2022. Cleveland Scene. Retrieved January 26, 2022, from https://m.clevescene.com/cleveland/yk11-results-dosage-side-effects-before-and-after-best-sarms-for-sale-2022/Content?oid=37669424
5. Admin, U. P. (2021, December 2). Myostatin inhibitor YK-11: The muscle growth breakthrough! Rochester Hills. University Pain Clinic of Rochester. Retrieved January 26, 2022, from http://universitypain.net/myostatin-inhibitor-yk-11-the-muscle-growth-breakthrough/
As and adult dietary supplement, take 1 capsule up to three times a day with meals. Do not exceed more than 3 capsules in 24 hour period of time
Consult your physician prior to use if you have or are at risk for high blood pressure, heart, kidney, thyroid, prostate or psychiatric disease, including anxiety, depression, seizure disoders, strokes or any other medical condition. Do not use this product if you have been diagnosed with androgen-sensitive cancers, high cholesterol or hypertension. Consult your physician prior to use if you are taking any other medications. Do not exceed the suggested dosage of 3 capsules in any single given 24 hour period time. Discontinue use if you experience rapid heartbeat, dizziness, vomiting, or other similar symptoms. Keep out of reach from children.
** These statements have not been evaluated bu the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Always Consult your physician before beginning any diet, supplement, or exercise regimen.